Product name : 7-Ethyl-10-Hydroxycamptothecin
Trival name : SN38, SN-38
Chemical name : 7-Ethyl-10-Hydroxy-20(S)-Camptothecin
CAS number : 86639-52-3
Molecular formula : C22H20N2O5
Molecular weight : 392.31
Molecular structure:
![](/en/eWebEditor/uploadfile/20110418144450430.gif)
Specifications: 90%-99%
Appearance : Yellow crystalline powder
Identification : IR, UV correspond with standard
Melting point : 228 -235 °C
Heavy metals : Not more than 10ppm
Assay : >= 98% (HPLC)
What is 7-Ethyl-10-hydroxy-camptothecin? 7-Ethyl-10-hydroxy-camptothecin for CPT derivative product of nearly pure white needle-like crystals, dissolved in dimethyl - Oxide, micro-soluble in methanol, ethanol, in the water and almost insoluble in chloroform, ethanol and DMF in the heat of the solubility of larger, Mp.224 ° C. mainly used for preparation of anticancer drug irinotecan hydrochloride. SN-38 and can also be VP-16, doxorubicin, Bleomycin in the treatment of non-small cell lung cancer, colorectal cancer, and so on.
Application 1. For laboratory research use only (content determination, identification, pharmacology experiment), shall not be used for medical diagnosis and not for other purposes. 2. In the experiments, used for identification, examination and content determination, impurities and related substances examination standard material. 3.Should as far as possible consistent with products concentrate formulation. |