Product Name: | Apigenin | ||
Product Type: | Main Products | ||
Usage: | Antioxidant, anticarcinogenic and hypotensive activity | ||
Clicks: | 5414 | ||
Release Time: | 2010-05-19 | ||
Introduction | |||
Name: Apigenin Synonyms: 4′,5,7-Trihydroxyflavone CAS Number: 520-36-5 Empirical Formula (Hill Notation): C15H10O5 Molecular Weight: 270.24 Beilstein Registry Number: 262620 MDL number: MFCD00006831 PubChem Substance ID: 24846790 EC Number: 208-292-3 Description Biochem/physiol Actions: A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2 /M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibitory effects on tumor promotion may also be due to inhibition of kinase activity and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I catalyzed DNA religation and enhance gap junctional intercellular communication. Other Notes: Inhibitor of human estrogen synthetase1 Properties product line BioChemika assay ≥95.0% (HPLC) total impurities ~2% water mp >300 °C(lit.) storage temp. −20°C Safety F 10 Hazard Codes Xi Risk Statements 36/37/38 Safety Statements 26-36 WGK Germany 3 RTECS LK9276000 |