Chlorogenic Acid - Staherb Natural Ingredients-Chlorogenic acid corosolic acid Icariin Amygdalin Ursolic acid

Product Name：

Chlorogenic Acid

Product Type：

Main Products

Usage：

Drugs, health care products, cosmetics, raw materials

Clicks：

9568

Release Time：

2010-03-02

Introduction

Specification: chlorogenic acid 5-98%（10% 25% 30% 50% 90%） (HPLC) 
Molecular formula: C₁₆H₁₈O₉ 
CAS No: 327-97-9 
Einecs No:206-325-6 
Molecular weight: 354.31 
Solubility: Good solubility in water 
Melting point:205-209 
Appearance: Fine crystal powder 
Color: White （chlorogenic acid 98% 99%） 
Specific Rotation [α]: -36° (c=1,H2O)

Density:1.28 g/cm3

Melting point:207 - 209 °C

Structure :

Chlorogenic acid   Chlorogenic acid is a phenolic natural product isolated from the

leaves and fruits of dicotyledonous plants,including the coffee bean. The ester of caffeic

acid with quinic acid,is one of the most abundant polyphenols in the human diet with coffee,

fruits and vegetables as its major sources. Its antioxidantand anticarcinogenic properties have

been well established in animal studies.lorogenic Acid

Function: 

a) Can be used as anti-infectious active ingredient 
b) Has wide anti-virus, anti-bacteria effects 
c) Has relatively lower toxicity and side-effects 
d) Has obvious anti-infectious effects. 
e) Due to its obvious anti-infectious effects, it not only can be used in pharmaceutical field

   but also can be used widely in many other fields like food, feed additives and cosmetics 
f) Chlorogenic Acid—Best ingredients for cosmetic product

   I. Strong Anti-oxidant ability

   II.100% water soluble

   III.Very stable at normal temperature

   IV.Pure white

   V. No hypersusceptibility
   VI.100% natural 
g)Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to

the prevention of Type 2 Diabetes Mellitus and cardiovascular disease. h)Chlorogenic acid has

been proven in animal studies in vitro to inhibit the hydrolysis of the glucose-6-phosphate

enzyme in an irreversible fashion.The studies also confirmed a reduction in blood glucose

evels and an increase in the intrahepatic concentrations of glucose-6-phosphate and of glycogen.

Description of chlorogenic acid: 
a) Has a wide range of biological effects, from insect resistance to human health 
b) An important factor in plant metabolism 
c) An antioxidant and has anti-fungi effectivity,stronger than the antibacterial 
effectivity 
d) An ester of caffeic acid and quinic acid, a major phenolic compound in coffee, 
the daily intake of coffee drinkers is 0.05-0.1g 
e)Strong antioxidants in vitro and could therefore be contribute to the prevention of disease

caused by free radicals Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major

phenolic compound in coffee, but is also found widespread in plants and can be isolated from the

leaves and fruit . This compound, long known as an antioxidant, also slows the release of glucose

into the bloodstream after a meal. 
f) Structurally, chlorogenic acid (CGA) is the ester formed between caffeic acid and (L)-quinic

aicd(1L-1(OH),3,4/5-tetrahydroxycyclohexanecarboxylic acid). Isomerisation  of the  quinic acid

in position 3, (3-CQA),4 (4-CQA) and 5 (5-CQA). Isomerisation at position 1 has not yet been

reported. Isomers of chlorogenic acid are found in potatoes. They are 4-O-caffeoylquinic acid

(crypto-chlorogenic acid), 5-O-caffeoylquinic acid (neo-chlorogenic acid), 3,4-dicaffeoylquinic

acid and 3,5-dicaffeoylquinic acid.