Luteolin Function |
发布时间:2020-10-31 信息来源:admin 发布人:admin 点击次数:937 |
Luteolin is a natural flavonoid found in many plants. It has a variety of pharmacological activities, such as anti-inflammatory, anti-allergic, uric acid-lowering, anti-tumor, anti-bacterial, anti-viral, etc. It is mainly used for cough, expectorant, anti-inflammatory, uric acid-lowering, cardiovascular disease treatment, and treatment of "muscle atrophic spinal cord side". Sclerosing", SARS, hepatitis, etc.
Luteolin Function
1.Luteolin is a hypoglycemic agent and improves insulin sensitivity. By promoting healthy glucose levels it is good for type 2 diabetics. 2.Acting as an antioxidant and protecting the body from dangerous free radicals; 3.. Externally luteolin can be used for skin allergic/inflammatory disorders and for skin cancer prevention; 4. Luteolin is a promising agent for use in ophthalmology.
Luteolin Application
1.Applied in food field, Luteolin is often used as food additives; 2. Applied in health product field, Luteolin is made into capsules with the function of vasodilatation; 3.Applied in pharmaceutical field, Luteolin can play the role of inflammation; 4.Applied in cosmetic field, Luteolin is often made into the products of losing weight.
MOA-Luteolin
1、Chromatographic conditions
Chromatographic column:Agilent Tc
-
C18, 250mm×4.6mm
5μm
Mobile phase: methanol,Water (88:12,v/v)
Column temperature:30℃
Flow rate:1mL/min
Detection wavelength:210nm
Injection volume:10μL
2、Solution preparation
1. Preparation of reference solution Precision weighed dry to constant weight
reference substance about 5mg in a 25 mL volumetric flask , Dissolve with
methanol。
2. Preparation of Sample Solution,accurately weighed extract samples in a
volumetric flask and add methanol,Ultrasonic oscillation 20min, Placed to
room temperature , with Methanol to volume , filtered through a 0.45μm
mmicroporous membrane,then get the obtain a sample solution。
3、DETERMINATION OF SAMPLES
In the chromatographic conditions, injection determination after
stable instrument, baseline is stable
4.Result
Assay % A x Ws x S R=----------------- x 100 As x W
---- As Reference substance peak area
---- A Total peak area in the sample of Butelin
--- Ws Sample volume of Reference sample(mg)
--- W Sample weight of the sample(mg)
--- S Reference substance
Luteolin HPLC Chromagram |